Table 1.

Demographics of the matched cohort

Variable	No ARDS (n = 12)	ARDS (n = 12)	P Value
Age, yr	10.9 [4.6, 17.3]	11.3 [4.4, 14.7]	0.544
Female, %	4 (33)	7 (58)	0.414
Pediatric Risk of Mortality III	11 [9, 15]	11.5 [9, 15.5]	0.547
Vasopressor score	14 [6, 19]	13 [4, 38]	0.424
Lactate, mmol/L	4.5 [2.7, 5.2]	2.4 [2.2, 3.7]	0.140
Sepsis etiology, %			0.883
Pulmonary	2 (17)	2 (17)
Blood	4 (33)	6 (50)
Abdomen	4 (33)	3 (25)
Genitourinary/renal	1 (8)	0
Skin/soft tissue	0	1 (8)
Central nervous system	1 (8)	0
Immunocompromised, %	5 (42)	6 (50)	1
Oxygenation
$\text{P}{\text{a}}_{\text{O}}{}_{{}_2}$/$\text{F}{\text{I}}_{{\text{O}}_2}$	366 [349, 467]	223 [153, 277]	0.012
Oxygenation index	3.1 [1.6, 3.8]	8.1 [5.3, 12]	<0.001
Berlin ARDS severity, %
Mild		6 (50)
Moderate		4 (33)
Severe		2 (17)
Nonpulmonary organ failures, %
Neurologic	0	0	1
Cardiovascular	12 (100)	12 (100)	1
Liver	3 (25)	6 (50)	0.400
Kidney	5 (42)	7 (58)	0.684
Hematologic	5 (42)	6 (50)	1
PICU mortality, %	1 (8)	5 (42)	0.059

ARDS, acute respiratory distress syndrome; PICU, pediatric intensive care unit.