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. 2022 Feb 11;9:814587. doi: 10.3389/fmed.2022.814587

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Copyright © 2022 Gavrielatou, Xourgia, Xixi, Mantelou, Ischaki, Kanavou, Zervakis, Routsi, Kotanidou and Siempos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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All-cause mortality of critically ill patients with COVID-19 receiving vitamin C on top of standard-of-care (vitamin C group) vs. standard-of-care alone (control group). Pooled risk ratio (RR) and 95% confidence intervals (CI) were calculated using a random effects model.