FIGURE 6.

Interleukin-17A aggravated brain tissue damage and reduced survival rate in E. coli-infected mice. (A) WT mice, IL-17A KO mice with or without adding recombinant IL-17A, were infected with E. coli, the histopathological changes in the brain were investigated by H&E staining. Scale bar indicates 50 μm. (B) Survival analysis curves for WT mice, IL-17A KO mice with or without adding recombinant IL-17A infected with E. coli. Data were collected and shown as Kaplan–Meier survival curves from 14 individual mice. *p < 0.05 and **p < 0.01.