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. 2022 Feb 24;8:78. doi: 10.1038/s41420-022-00879-9

Fig. 6. Overexpression of c-Myb in vivo inhibits cisplatin-induced cochlear HC apoptosis.

Fig. 6

A, B Representative images of TUNEL staining and cell counting showing that the numbers of TUNEL/Myosin7a double-positive IHCs and OHCs in the basal turns were increased significantly after cisplatin exposure in vivo compared to the vehicle control group, while the transfection of AAV-c-Myb led to a significantly reduced number of TUNEL/myosin7a double-positive HCs in the cisplatin + AAV-c-Myb group compared to the cisplatin + AAV-ie group. Scale bar = 20 μm. **p < 0.01, ***p < 0.001, n = 6 for each group.