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. 2022 Feb 24;13:1036. doi: 10.1038/s41467-022-28626-9

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b UMAP projection of cell clusters shown by cell population (a) and origin of individual cells (b). c Feature plots for canonical markers of different cell populations. d, e UMAP projection of the origin of individual cells (d) and OPC lineage subclusters (e). f Violin plots of markers enriched in specific oligodendrocyte subpopulation. Gene expression level plotted as normalized counts. GW gestational weeks. (n = 3 donors; 2 females, aged 95 (504 cells) and 96 years (118 cells); 1 male, aged 72 years (116 cells)).