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. 2022 Feb 24;5:166. doi: 10.1038/s42003-022-03110-8

Fig. 2. HM2-16F is bactericidal towards mycobacteria in vitro and in macrophages.

Fig. 2

a Structure of HM2-16F. b Survival of M. tuberculosis after treatment with: isoniazid (INH 2 μM, 10× MIC), HM2-16F (20 μM, 5× MIC) and bedaquiline (BDQ 2 μM, 10X MIC). c Survival of M. bovis BCG in human THP-1 macrophages after treatment with 5 μM HM2-16F and BDQ. Error bars indicate standard deviation from three biological independent experiments.