Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 24;13:1046. doi: 10.1038/s41467-022-28718-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Scatter plot showing the positive association between the log-transformed values for maximum catalytic iron (Fe_c ^max) concentration per patient and the corresponding SOFA scores of that day. b Boxplots showing the log-transformed Fe_c ^max values of patients who passed away within 30 days and those who survived. c Boxplots showing the log-transformed Fe_c ^max values of all patients grouped by the presence of sepsis, septic shock, or non-septic MODS. d Scatter plot showing the positive association between the log-transformed values for maximum MDA (MDA^max) concentration per patient and the corresponding SOFA scores of that day. e Boxplots showing the log-transformed MDA^max values of patients who passed away within 30 days and those who survived. f Boxplots showing the log-transformed MDA^max values of all patients grouped by the presence of sepsis, septic shock, or non-septic MODS. g Boxplots showing the log-transformed Fe_c values on the day of MDA^min (light blue) and MDA^max (dark blue) for each individual patient (gray lines). h Histogram representing the density distribution of MDA^max values for both the patients who survived (black) versus those who died (red) within 30 days. i Survival curves representing the patients with values of MDA^max < 2.85 µM (light blue) and MDA^max ≥ 2.85 µM (dark blue). Data were analyzed using Spearman’s rank correlation coefficient for continuous variables (a, d), two-sided Wilcoxon–Mann–Whitney (b, e), Kruskal–Wallis (omnibus), and two-sided Wilcoxon–Mann–Whitney (pairwise) test (c, f), Paired two-sided Wilcoxon signed-rank test (g) and two-sided Log-Rank test (i). The full range of observations are plotted on all the boxplots, where the bottom, center, and top of the bounding box represent respectively the 25th, 50th, and 75th percentiles. The whiskers extend to a maximum of 1.5 times the interquartile range (IQR = Q3 − Q1) beyond the bounding box. N = 176 for all graphs. Source data are provided as a Source Data file.