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. 2022 Feb 11;10:830671. doi: 10.3389/fchem.2022.830671

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Copyright © 2022 Hintze, Schnabelrauch and Rother.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemical structure of a HA disaccharide repeating unit showing the reactive functional groups (A) and presentation of simplified HA formulas with reaction centers involved in the different modifications (B).