TABLE 1.
Description | Gene markers | THCA | PRAD | PAAD | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
None | Purity | None | Purity | None | Purity | ||||||||
Cor | Pvalue | Cor | Pvalue | Cor | Pvalue | Cor | Pvalue | Cor | Pvalue | Cor | Pvalue | ||
CD8+ T cell | CD8A | −0.202 | a | −0.192 | a | −0.314 | a | −0.254 | a | −0.292 | a | −0.233 | b |
CD8B | −0.152 | a | −0.143 | b | −0.157 | a | −0.124 | c | −0.279 | a | −0.217 | b | |
T cell (general) | CD3D | −0.26 | a | −0.25 | a | −0.153 | a | −0.071 | 0.146 | −0.19 | c | −0.122 | 0.112 |
CD3E | −0.305 | a | −0.295 | a | −0.259 | a | −0.2 | a | −0.238 | b | −0.17 | c | |
CD2 | −0.316 | a | −0.303 | a | −0.253 | a | −0.16 | b | −0.292 | a | −0.224 | b | |
B cell | CD19 | −0.183 | a | −0.167 | a | −0.059 | 0.187 | −0.015 | 0.759 | −0.186 | c | −0.118 | 0.123 |
CD79A | −0.209 | a | −0.194 | a | −0.153 | a | −0.089 | 0.068 | −0.194 | b | −0.123 | 0.109 | |
Monocyte | CD86 | −0.404 | a | −0.393 | a | −0.414 | a | −0.336 | a | −0.399 | a | −0.332 | a |
CSF1R | −0.346 | a | −0.343 | a | −0.37 | a | −0.299 | a | −0.347 | a | −0.289 | a | |
TAM | CCL2 | −0.26 | a | −0.244 | a | −0.223 | a | −0.165 | a | −0.282 | a | −0.253 | a |
CD68 | −0.358 | a | −0.34 | a | −0.35 | a | −0.289 | a | −0.228 | b | −0.157 | c | |
IL10 | −0.292 | a | −0.279 | a | −0.338 | a | −0.251 | a | −0.258 | a | −0.208 | b | |
M1 Macrophage | IRF5 | −0.324 | a | −0.317 | a | −0.234 | a | −0.263 | a | 0.027 | 0.719 | 0.058 | 0.454 |
PTGS2 | −0.319 | a | −0.31 | a | −0.268 | a | −0.179 | a | −0.237 | b | −0.253 | a | |
M2 Macrophage | CD163 | −0.335 | a | −0.32 | a | −0.414 | a | −0.343 | a | −0.438 | a | −0.377 | a |
VSIG4 | −0.353 | a | −0.345 | a | −0.379 | a | −0.303 | a | −0.347 | a | −0.278 | a | |
MS4A4A | −0.334 | a | −0.321 | a | −0.363 | a | −0.297 | a | −0.379 | a | −0.309 | a | |
Neutrophils | CEACAM8 | −0.196 | a | −0.197 | a | 0.004 | 0.922 | 0.017 | 0.724 | −0.059 | 0.433 | −0.005 | 0.95 |
ITGAM | −0.411 | a | −0.401 | a | −0.361 | a | −0.309 | a | −0.285 | a | −0.191 | c | |
CCR7 | −0.293 | a | −0.276 | a | −0.274 | a | −0.217 | a | −0.178 | c | −0.124 | 0.106 | |
Dendritic cell | HLA-DPB1 | −0.305 | a | −0.295 | a | −0.119 | b | −0.057 | 0.246 | −0.232 | b | −0.159 | c |
HLA-DQB1 | −0.291 | a | −0.295 | a | −0.198 | a | −0.147 | b | −0.243 | b | −0.189 | c | |
HLA-DRA | −0.377 | a | −0.365 | a | −0.351 | a | −0.295 | a | −0.35 | a | −0.289 | a | |
HLA-DPA1 | −0.364 | a | −0.351 | a | −0.339 | a | −0.257 | a | −0.356 | a | −0.3 | a | |
CD1C | −0.336 | a | −0.319 | a | −0.319 | a | −0.242 | a | −0.199 | b | −0.14 | 0.067 | |
NRP1 | −0.258 | a | −0.245 | a | −0.29 | a | −0.271 | a | −0.471 | a | −0.439 | a | |
ITGAX | −0.363 | a | −0.348 | a | −0.299 | a | −0.277 | a | −0.185 | c | −0.091 | 0.236 |
p < 0.05.
p < 0.01.
p < 0.001.