. 2022 Feb 11;13:822261. doi: 10.3389/fgene.2022.822261

TABLE 2.

Correlation analysis between ALKBH7 and gene markers of different types of T cells in TIMER.

Description	Gene markers	THCA				PRAD				PAAD
		None		Purity		None		Purity		None		Purity
		Cor	P	Cor	P	Cor	P	Cor	P	Cor	P	Cor	P
Th1	TBX21	−0.199	^a	−0.192	^a	−0.2	^a	−0.17	^a	−0.194	^b	−0.143	0.062
	STAT4	−0.317	^a	−0.317	^a	−0.281	^a	−0.216	^a	−0.207	^b	−0.179	^c
	STAT1	−0.451	^a	−0.436	^a	−0.421	^a	−0.339	^a	−0.355	^a	−0.302	^a
	IFNG	−0.231	^a	−0.221	^a	−0.206	^a	−0.144	^b	−0.277	^a	−0.238	^b
	TNF	−0.236	^a	−0.229	^a	−0.261	^a	−0.168	^a	−0.125	0.096	−0.076	0.32
	IL12A	−0.064	0.152	−0.057	0.206	−0.21	^a	−0.155	^b	−0.127	0.09	−0.108	0.159
	IL12B	−0.254	^a	−0.245	^a	−0.211	^a	−0.145	^b	−0.134	0.075	−0.101	0.187
Th1-like	HAVCR2	−0.395	^a	−0.382	^a	−0.364	^a	−0.3	^a	−0.352	^a	−0.28	^a
	IFNG	−0.231	^a	−0.221	^a	−0.206	^a	−0.144	^b	−0.277	^a	−0.238	^b
	CXCR3	−0.15	^a	−0.136	^a	−0.226	^a	−0.185	^a	−0.017	0.825	0.046	0.549
	BHLHE40	−0.375	^a	−0.367	^a	−0.345	^a	−0.311	^a	−0.097	0.196	−0.091	0.238
	CD4	−0.394	^a	−0.384	^a	−0.4	^a	−0.322	^a	−0.337	^a	−0.268	^a
Th2	GATA3	−0.077	0.082	−0.058	0.199	−0.127	^b	−0.035	0.479	−0.157	^c	−0.119	0.122
	STAT6	−0.301	^a	−0.285	^a	−0.308	^a	−0.269	^a	−0.034	0.65	−0.019	0.806
	STAT5A	−0.273	^a	−0.266	^a	−0.24	^a	−0.164	^a	−0.072	0.339	−0.006	0.942
	IL13	−0.074	0.094	−0.071	0.116	−0.061	0.177	−0.088	0.073	−0.058	0.441	−0.049	0.521
Th17	STAT3	−0.356	^a	−0.336	^a	−0.449	^a	−0.385	^a	−0.338	^a	−0.298	^a
Th17	IL17A	−0.135	^a	−0.13	^b	−0.139	^b	−0.028	0.565	−0.235	^b	−0.228	^b
Tfh	BCL6	−0.231	^a	−0.202	^a	−0.316	^a	−0.306	^a	−0.26	^a	−0.238	^b
Tfh	IL21	−0.144	^b	−0.133	^b	−0.139	^b	−0.116	^c	−0.089	0.234	−0.048	0.532
Treg	FOXP3	−0.377	^a	−0.363	^a	−0.332	^a	−0.337	^a	−0.264	^a	−0.199	^b
	CCR8	−0.421	^a	−0.402	^a	−0.451	^a	−0.396	^a	−0.392	^a	−0.342	^a
	STAT5B	−0.209	^a	−0.189	^a	−0.465	^a	−0.409	^a	−0.126	0.093	−0.127	0.098
	TGFB1	−0.05	0.264	−0.042	0.359	−0.179	^a	−0.193	^a	0.07	0.353	0.133	0.083
Resting Treg	FOXP3	−0.377	^a	−0.363	^a	−0.332	^a	−0.337	^a	−0.264	^a	−0.199	^b
Resting Treg	IL2RA	−0.414	^a	−0.404	^a	−0.414	^a	−0.356	^a	−0.397	^a	−0.334	^a
Effector Treg	FOXP3	−0.377	^a	−0.363	^a	−0.332	^a	−0.337	^a	−0.264	^a	−0.199	^b
T-cell	CCR8	−0.421	^a	−0.402	^a	−0.451	^a	−0.396	^a	−0.392	^a	−0.342	^a
T-cell	TNFRSF9	−0.38	^a	−0.361	^a	−0.454	^a	−0.377	^a	−0.362	^a	−0.309	^a
Effector	CX3CR1	−0.17	^a	−0.162	^a	−0.383	^a	−0.262	^a	−0.262	^a	−0.236	^b
T-cell	FGFBP2	0.055	0.217	0.051	0.259	−0.118	^b	−0.094	0.056	−0.22	^b	−0.196	^c
T-cell	FCGR3A	−0.336	^a	−0.329	^a	−0.38	^a	−0.317	^a	−0.388	^a	−0.326	^a
Naive T-cell	CCR7	−0.293	^a	−0.276	^a	−0.274	^a	−0.217	^a	−0.178	^c	−0.124	0.106
Naive T-cell	SELL	−0.355	^a	−0.352	^a	−0.4	^a	−0.331	^a	−0.249	^a	−0.183	^c
Effector memory	DUSP4	−0.29	^a	−0.278	^a	−0.162	^a	−0.153	^a	−0.111	0.137	0.09	0.242
T-cell	GZMK	−0.253	^a	−0.242	^a	−0.258	^a	−0.19	^a	−0.216	^b	−0.149	0.052
T-cell	GZMA	−0.242	^a	−0.235	^a	−0.228	^a	−0.151	^b	−0.222	^b	−0.173	^c
Resident memory	CD69	−0.324	^a	−0.311	^a	−0.389	^a	−0.306	^a	−0.335	^a	−0.297	^a
T-cell	CXCR6	−0.282	^a	−0.269	^a	−0.292	^a	−0.188	^a	−0.339	^a	−0.283	^a
T-cell	MYADM	−0.144	^a	−0.123	^b	−0.335	^a	−0.306	^a	−0.186	^c	−0.159	^c
General memory	CCR7	−0.293	^a	−0.276	^a	−0.274	^a	−0.217	^a	−0.178	^c	−0.124	0.106
T-cell	SELL	−0.355	^a	−0.352	^a	−0.4	^a	−0.331	^a	−0.249	^a	−0.183	^c
T-cell	IL7R	−0.415	^a	−0.4	^a	−0.458	^a	−0.394	^a	−0.425	^a	−0.38	^a
Exhausted T cell	PDCD1	−0.152	^a	−0.154	^a	−0.088	^c	−0.072	0.142	−0.117	0.119	−0.044	0.568
	CTLA4	−0.317	^a	−0.304	^a	−0.151	^a	−0.115	^c	−0.227	^b	−0.159	^c
	LAG3	−0.211	^a	−0.207	^a	−0.031	0.486	0.001	0.98	−0.074	0.323	−0.047	0.543
	HAVCR2	−0.395	^a	−0.382	^a	−0.364	^a	−0.3	^a	−0.352	^a	−0.28	^a
	GZMB	−0.231	^a	−0.23	^a	−0.162	^a	−0.114	^c	−0.33	^a	−0.273	^a
	CXCL13	−0.264	^a	−0.262	^a	−0.192	^a	−0.147	^b	−0.218	^b	−0.161	^c
	LAYN	−0.073	0.098	−0.074	0.101	−0.237	^a	−0.189	^a	−0.217	^b	−0.162	^c

p < 0.05.

p < 0.01.

p < 0.001.