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. 2022 Feb 11;12:843299. doi: 10.3389/fonc.2022.843299

Figure 1.

Figure 1

3D-modeling of p.L747P conformation (A) and crystal structure of EGFR wild type kinase domain in complex with dacomitinib (B). ATP-binding pocket in the activating kinase domain of EGFR wild type (C) and p.L747P conformation (D).