Skip to main content
. 2022 Feb 11;9:803650. doi: 10.3389/fcvm.2022.803650

Table 1.

Comparison of clinical cardiovascular outcomes among smokers and non-smokers.

References Pt number Pt characteristics Parameter Results
MC Cruz et al. (11) 2727 ACS Current smokers
Never smokers
Current smokers received more evidence-based treatments and had less in-hospital complications, in-hospital mortality and adverse outcomes at 1 year. More frequent percutaneous coronary intervention at 1 year was noted in current smoker
Weisz et al. (12) 2082 AMI Former smokers
Current smokers
Never smokers
The “smoker's paradox” extends to patients undergoing primary PCI for AMI, with increased survival seen in current smokers
Redfors et al. (13) 2564 STEMI Recent smokers
Never smokers
In the present large-scale individual patient-data pooled analysis, recent smoking was unrelated to infarct size or microvascular obstruction, but was associated with a worse prognosis after primary PCI in STEMI.
Steele et al. (14) 1796 STEMI Current smokers
Ex-smokers
Never-smokers
No evidence of an association between mortality and smoking status in patients with acute STEMI treated with PCI, and thus no
evidence of a “smoker's paradox.”
Ciccarelli et al. (15) 713 STEMI Current smokers
Non-smokers
Not being a current smoker and ongoing DAPT at admission, in patients with STEMI undergoing PPCI, represent independent negative prognostic value.
Symons et al. (16) 471 STEMI Smokers
Non-smokers
Smoking is strongly and independently associated with intramyocardial hemorrhage at baseline. smoking was an independent predictor of more favorable post-infarction LV remodeling.
Robertson et al. (17) 13819 NSTE-ACS Smokers
Non-smokers
Smoking to be an independent predictor of higher 1-year mortality in patients presenting with NSTE-ACS and angiography study demonstrates CAD in smokers that is comparable to that in non-smokers but evident 1 decade earlier.
Amor-Salamanca et al. (18) 563 NSTE-ACS Smokers
Non-smokers
Confirms the “smoking paradox” amongst NSTACS patients, which is explained by the lower prevalence of previous myocardial infarction, diabetes or multivessel disease

Pt number, patient number; Pt characteristic, patient characteristics; ACS, acute coronary syndrome; AMI, acute myocardial infarction; STEMI, ST-elevation myocardial infarction; NSTE-ACS, non-ST elevation acute coronary syndrome.