Table 5.
Significant crude and adjusted predictors of outcome in Cox proportion hazard model for MI, All-death, CV-death, Repeated PCI.
| Variables | MI | All-death | CV-death | Repeated PCI | ||||
|---|---|---|---|---|---|---|---|---|
| Crude HR (95%C.I.) | Adjusted HR (95%C.I.)a | Crude HR (95%C.I.) | Adjusted HR (95%C.I.)a | Crude HR (95%C.I.) | Adjusted HR (95%C.I.)a | Crude HR (95%C.I.) | Adjusted HR (95%C.I.)a | |
| Smoking | 0.73 (0.40–1.33) | 1.39 (0.53–3.68) | 0.71 (0.48–1.03) | 1.71 (1.11–2.62)* | 0.79 (0.50–1.25) | 1.58 (0.91–2.72) | 1.54 (1.24–1.92)** | 1.46 (1.17–1.83)** |
| Age | 1.02 (0.99–1.05) | 1.01 (0.96–1.06) | 1.03 (1.02–1.05)** | 1.00 (0.99–1.02) | 1.03 (1.01–1.05)** | 1.01 (0.99–1.04) | 1.00 (0.99–1.01) | 1.01 (1.00–1.02) |
| DM | 1.49 (0.86–2.59) | 1.14 (0.41–3.15) | 1.31 (0.94–1.83) | 1.46 (1.02–2.09)* | 1.41 (0.93–2.16) | 1.21 (0.74–1.98) | 1.23 (0.99–1.54) | 1.06 (0.85–1.33) |
| MI hx | 2.77 (1.50–5.12)** | 1.47 (0.42–5.17) | 3.14 (2.18–4.52)** | 1.68 (1.12–2.51)* | 3.79 (2.35–6.11)** | 1.51 (0.86–2.65) | 1.26 (0.99–1.60) | 1.22 (0.97–1.55) |
| CKD | 1.29 (0.70–2.39) | 1.27 (0.37–4.33) | 2.39 (1.59–3.60)** | 1.54 (0.97–2.47) | 1.92 (1.15–3.19)* | 1.66 (0.87–3.16) | 1.50 (1.18–1.91)** | 1.36 (1.07–1.74)* |
| Stroke | 1.76 (0.69–4.48) | 1.54 (0.40–5.97) | 1.51 (0.88–2.59) | 1.46 (0.81–2.63) | 1.86 (1.01–3.43)* | 1.33 (0.68–2.59) | 0.94 (0.56–1.58) | 1.32 (0.76–2.31) |
| CPP | 1.00 (0.99–1.01) | 1.00 (0.97–1.02) | 1.00 (0.99–1.01) | 0.99 (0.99–1.00) | 1.00 (0.99–1.01) | 0.99 (0.98–1.00) | 1.00 (0.99–1.00) | 0.99 (0.98–1.00) |
| Syntax core | 1.04 (1.01–1.06)* | 1.04 (0.99–1.09) | 1.02 (1.01–1.04)** | 1.00 (0.98–1.02) | 1.03 (1.01–1.05)* | 1.01 (0.99–1.03) | 1.01 (0.99–1.02) | 1.02 (1.01–1.04)** |
| DES | 0.46 (0.22–0.96)* | 1.30 (0.23–7.40) | 0.83 (0.56–1.24) | 0.76 (0.49–1.18) | 0.60 (0.36–1.02) | 1.23 (0.67–2.26) | 0.99 (0.78–1.25) | 1.09 (0.85–1.40) |
| Aspirin | 1.62 (0.49–5.19) | 0.65 (0.04–9.84) | 1.16 (0.67–1.99) | 0.55 (0.31–0.99)* | 1.33 (0.64–2.78) | 0.43 (0.19–0.99)* | 1.59 (0.99–2.54) | 0.72 (0.44–1.16) |
| P2Y12 inhibit | 1.48 (0.67–3.28) | 1.48 (0.30–7.29) | 1.11 (0.69–1.79) | 1.65 (0.97–2.82) | 2.19 (1.03–4.64)* | 2.31 (0.89–6.00) | 1.59 (1.16–2.17)** | 1.74 (1.25–2.42)** |
| BB | 1.14 (0.66–1.98) | 0.78 (0.27–2.27) | 0.68 (0.48–0.96)* | 0.94 (0.65–1.36) | 0.61 (0.39–0.95)* | 0.85 (0.51–1.44) | 1.15 (0.93–1.41) | 0.92 (0.75–1.16) |
| CCB | 0.83 (0.42–1.64) | 1.62 (0.47–5.63) | 0.66 (0.43–1.00) | 0.98 (0.63–1.51) | 0.58 (0.33–1.03) | 1.09 (0.57–2.08) | 1.05 (0.83–1.33) | 0.99 (0.78–1.27) |
| ACEI | 1.19 (0.67–2.12) | 0.51 (0.24–1.13) | 0.72 (0.49–1.05) | 0.52 (0.35–0.79)** | 0.62 (0.38–1.01) | 0.66 (0.37–1.19) | 0.59 (0.46–0.75)** | 0.44 (0.34–0.57)** |
| Statin | 0.50 (0.27–0.93)* | 0.54 (0.16–1.82) | 0.37 (0.24–0.57)** | 0.89 (0.55–1.43) | 0.41 (0.24–0.70)** | 0.53 (0.28–0.99)* | 0.71 (0.57–0.88)** | 0.68 (0.54–0.85)** |
DM, diabetes Mellitus; MI hx, Previous history of myocardial infarction; CKD, chronic kidney disease; CPP, central pulse pressure; SYNTAX score, Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery score; DES, drug-eluting stent; P2Y12 inhibit, P2Y12 receptor inhibitor of platelet; BB, beta-blockers; CCB, calcium channel blocker; ACEI, angiotensin-converting enzyme inhibitor.
a
Adjusted for MI, all-death, CV-death, and repeated PCI.
*
P < 0.05,
**
P < 0.01.