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Clinically actionable mutations detected in stage 4-4B cases and their concordance of detection with tissue EGFR tests.
| Stage | Mutation (HGVSp) | AF (%) | Concordant with tissue EGFR |
|---|---|---|---|
| 4B | EGFR p.E746_A750del | 7.15 | Yes |
| 4 | EGFR p.E746_A750del | 0.73 | Yes |
| 4 | KRAS p.G12D | 12.36 | NA |
| 4 | EGFR p.L747_A750delinsP | 0.98 | Yes |
| 4 | BRAF p.K601E | 12.45 | NA |
| 4 | KRAS p.G12D | 27.17 | NA |
| 4 | EGFR p.E746_A750del | 0.33 | Yes |
| 4 | EGFR p.E746_S752delinsV | 50.7 | Yes |
| 4 | KRAS p.G12D | 3.32 | NA |
NA, not applicable as not tested by tissue EGFR.
