Skip to main content
. 2022 Feb 11;13:839585. doi: 10.3389/fmicb.2022.839585

TABLE 1.

Summarization of virus-induced macrophage polarization.

Virus Family Viral genome type Polarized phenotype References
Junin virus (JUNV) Arenaviridae −ssRNA Attenuated Candid 1 strain: M1; Pathogenic P strain: M2 Ferrer et al., 2019
Influenza virus (IV) Orthomyxoviridae Segmented −ssRNA M1 Zhang et al., 2018
Severe fever with thrombocytopenia syndrome virus (SFTSV) Bunyaviridae Segmented −ssRNA M2 Zhang L. et al., 2019
Foot-and-mouth disease virus (FMDV) Picornaviridae +ssRNA M1 Sebastian et al., 2020
Coxsackievirus B3 (CVB3) Picornaviridae +ssRNA Male: M1; Female: M2 Li et al., 2009
Porcine reproductive and respiratory syndrome virus (PRRSV) Arteriviridae +ssRNA M2 Wang et al., 2017
West Nile virus (WNV) Flaviviridae +ssRNA M1 Stone et al., 2019
Hepatitis C virus (HCV) Flaviviridae +ssRNA M2 Bility et al., 2016
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Coronaviridae +ssRNA M2 Boumaza et al., 2021
Human immunodeficiency virus type 1 (HIV-1) Retroviridae +ssRNA Acute phase: M1; Chronic phase: M2 Burdo et al., 2015
Hepatitis B virus (HBV) Hepadnaviridae cccDNA M2 Bility et al., 2014
Epstein-Barr virus (EBV) Herpesviridae dsDNA M2 Zhang B. et al., 2020
Human cytomegalovirus (HCMV) Herpesviridae dsDNA M1 Chan et al., 2008
African swine fever virus (ASFV) Asfarviridae dsDNA M1 Tatoyan et al., 2020