FIGURE 2.

Biofilm‐dispersing wound gel (BDWG) did not affect wound closure. Full‐thickness excision wounds were generated on the dorsum of adult mice (3/group) and were covered with untreated gauze (UT), gauze spread with PEG (PT), or gauze spread with BDWG (BT). All wounds were then covered with transparent adhesive dressing. At 1, 3, 7, 10, 13, 16, and 19 days post‐injury/treatment, the adhesive dressings and the gauzes were removed and the wounds examined. A, Macroscopic changes within the skin wounds. All animals were observed for changes of wound appearance. Representative animals were chosen and the same animal was photographed for the series. B, Percentage of wound closure. C, Line graph of the total wound surface area (cm²). Values in panels B and C represent the means for three animals ± SEM. Significant differences among treatments and from day‐to‐day changes within a treatment were assessed using two‐way analysis of variance (ANOVA) with Tukey's multiple comparisons post‐test; *, P < .05; **, P < .01