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. 2022 Feb 24;9(3):e1149. doi: 10.1212/NXI.0000000000001149

Figure 2. Concentration of Neutrophil-Derived cfDNA Is Elevated in Patients With NMOSD.

Figure 2

(A) Schematic representation of the calculation of tissue contribution based on tissue-specific methylation profiles. (B) Heat map visualization of cfDNA concentration from different sources. (C) cfDNA concentration derived from the neutrophils in NMOSD plasma (n = 10) or healthy control plasma (n = 8). The Mann-Whitney U test was used to determine statistical significance. ***p < 0.002. HC = healthy control.