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. 2022 Feb 18;23(4):2288. doi: 10.3390/ijms23042288
ADC Antibody-drug conjugate
ADCC Antibody-dependent cell-mediated cytotoxicity
AI Aromatase inhibitor
Akt Protein kinase B
AMPK Adenosine monophosphate-activated protein kinase
APC Antigen-presenting cell
ATM Ataxia telangiectasia-mutated kinase
ATP Adenosine triphosphate
BC Breast cancer
BRCA Breast cancer-associated protein
CDK Cyclin-dependent kinase
CK Cytokeratins
CNS Central nervous system
DNA Deoxyribonucleic acid
dsDNA Double-stranded deoxyribonucleic acid
EGFR/ERB Epidermal growth factor receptor
ER Estrogen receptor
FDA Food and drug administration
gBRCA Germline breast cancer associated protein gene
GM-CSF Granulocyte-macrophage colony-stimulating factor
HER1 Human epidermal growth factor receptor 1
HER2 Human epidermal growth factor receptor 2
HER3 Human epidermal growth factor receptor 3
HER4 Human epidermal growth factor receptor 4
HLA-A2 Human leukocyte antigen-A2
HR Hormone receptor
HRR Homologous recombination repair
LKB1 Liver kinase B1
LumA Luminal-A
LumB Luminal-B
mTOR Mammalian target of rapamycin
NAD+ Nicotinamide adenine dinucleotide
NHEJ Non-homologous end joining
PAM PI3K/Akt/mTOR pathway
PARP Poly-ADP-ribose polymerase
PARPi Poly-ADP-ribose polymerase inhibitor
PARylation Poly-ADP-ribosylation
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha gene
PIP2 Phosphatidylinositol-4,5-biphosphate
PIP3 Phosphatidylinositol-3,4,5-triphosphate
PI3K Phosphoinositide 3-kinase
PR Progesterone receptor
PD-1 Programmed cell death protein 1
PD-L1 Programmed cell death ligand 1
PTEN Phosphatase and tensin homolog
Rb Retinoblastoma protein
RTK Receptor tyrosine kinase
SERD Selective estrogen receptor degrader
SERM Selective estrogen receptor modulator
TAA Tumor-associated antigen
T-DM1 Trastuzumab emtansine
T-DXd Trastuzumab deruxtecan
TGF-β Transforming growth factor beta
TKI Tyrosine kinase inhibitor
TNBC Triple-negative breast cancer
Trop-2 Trophoblast cell-surface antigen 2