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. 2022 Feb 17;14(2):435. doi: 10.3390/pharmaceutics14020435

Table 4.

Examples of recently developed metal-based nanosystems for application in cancer magnetic hyperthermia.

Material Morphology Properties Ref.
Carbothermal treated iron oxide Nanospheres with oxygen vacancies
  • Size range: 5.1–225.6 nm

  • Saturation magnetization: 5.8–31.3 emu/g

  • Specific absorption rate: up to 71.6 W/g

[157]
Magnetite Nanospheres
(coated with dextran)
  • Average size: 10 nm

  • Saturation magnetization: 40–60 emu/g

  • Specific power absorption: 132 W/g

[158]
Zn-substituted magnetite Irregular hexagonal nanoparticles
(coated with citric acid and pluronic F127)
  • Mean hydrodynamic size: 436–626 nm

  • Specific loss power: up to 539 W/g

  • Intrinsic loss power: up to 7.26 nHm2kg−1

[159]
Gd-doped maghemite Nanoparticles of almost spherical shape along with some aggregation
  • Size range: 8.73–11.06 nm

  • Saturation magnetization: 39.35–52.13 emu/g

  • Specific absorption rate: up to 140 W/g

[160]
Silver-iron oxide composite Irregular-shaped particles agglomerated to some extent
  • Size range: 2–24 nm

  • Specific loss power: up to 43 W/g

  • Intrinsic loss power: up to 0.81 nHm2kg−1

[161]
Iron oxide Cuboidal-shaped nanoparticles (functionalized with CTAB)
  • Average edge length: ~80 nm

  • Saturation magnetization: 71 emu/g

  • Specific loss power: up to ~1036 W/g

[162]
Cobalt ferrite Nanospheres
(coated with chitosan)
  • Average size: 13 nm

  • Saturation magnetization: ~62 emu/g

  • Specific absorption rate: up to 105 W/g

[163]
Copper ferrite Mesoporous spherical structures
  • Hydrodynamic size: ~91.2 nm

  • Saturation magnetization: ~32.7 emu/g

  • Specific absorption rate: up to ~192 ± 7 W/g

[164]
Copper ferrite Pseudo-cubical shaped particles
  • Hydrodynamic size: ~25.6 nm

  • Saturation magnetization: ~24.5 emu/g

  • Specific absorption rate: up to ~116 ± 6 W/g

[164]
Manganese ferrite Uniform nanospheres with some agglomeration
  • Average size: ~25 nm

  • Saturation magnetization: 54.18–59.67 emu/g

  • Specific absorption rate: 217.62 W/g

[165]