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. 2022 Feb 11;23(4):1989. doi: 10.3390/ijms23041989
LOAD Late-onset Alzheimer’s disease
AD Alzheimer’s disease
β-amyloid peptides
PAI-1 Plasminogen activator inhibitor 1
RS Replicative senescence
SIPS Stress-induced premature senescence
SASP Senescence-associated secretory phenotype
SA-β-gal Senescence-associated β-galactosidase
pRb Phosphorylated retinoblastoma protein
SAHFs Senescence-associated heterochromatin foci
SDFs Senescence-associated DNA damage foci
mH2A MacroH2A
HSCs Hematopoietic stem cells
NFTs Neurofibrillary tangles
MCI Mild cognitive impairment
LTL Leukocyte telomere length
APP Amyloid precursor protein
PS1 Presenilin 1
OPCs Oligodendrocyte precursor cells
HMGB1 High-mobility group box 1
TERT Telomerase reverse transcriptase
TERC Telomerase RNA component
ATM Ataxia-telangiectasia mutated
FAD Familial AD
VEGF-1 Vascular endothelial growth factor 1
NSPCs Neural stem/progenitor cells
ROS Reactive oxygen species
NLRP3 NLR family pyrin domain containing 3
DAM Disease-associated microglia
tPA Tissue-type plasminogen activator
uPA Urokinase-type plasminogen activator inhibitor
ATII Alveolar type II cells
TGF-β1 Transforming growth factor β1
NSC Neuronal stem cell