Table 2.

Comparison of various types of wound dressings.

Types of Wound Dressings	Advantages	Disadvantages	Highlights
Nanofibers	They possess a structure that mimics ECM, making them suitable for skin wound healing and regeneration. They are frequently formulated using efficient and easily employed electrospinning techniques.	It is not easy to produce nanofibers less than 10 nm in diameter.	The SEM micrographs of nanofibers loaded with bioactive agents display bead-free morphology that mimics ECM, making these wound dressings appropriate for providing an environment for cell proliferation and adhesion to accelerate the diabetic wound healing process.
Films and Membranes	These wound dressings are transparent, showing that the wound healing process can be observed without removing them. They also display good mechanical performance.	They are not suitable for exuding wounds due to their inability to absorb a large volume of biological fluids.	The mechanical properties of films and membranes were like those of human skin, making them skin compatible and easily handled during diabetic wound management.
Hydrogels	They are used as potential drug delivery systems in wound dressing applications and display other interesting properties such as high porosity, high swelling capacity, excellent biocompatibility, etc.	The biopolymer hydrogel dressings demonstrate poor mechanical performance that makes them not compatible with the human skin.	The drug release profiles were controlled release of bioactive agents from the polymeric hydrogels, resulting in an improved wound healing process. The high porosity of the hydrogels led to good swelling capability.
Foams and Wafers	These wound dressings exhibit high porosity that could provide cell growth and adhesion to accelerate the wound healing process.	They are not suitable for dry wounds.	The WVTR experiments of foams and wafers loaded with drugs exhibited moderate WTVR that can provide appropriate moisture to accelerate the healing of diabetic wounds.
Sponges and Bandages	These wound dressings are also displayed high porosity that could offer suitable gaseous permeation, superior cell proliferation, migration, and attachment for the accelerated wound healing process.	The very high porosity of the polymeric sponges or bandages can result in high uptake of wound exudate and high WVTR that may cause wound dehydration.	Polymeric sponges and bandages were mostly loaded with antibacterial agents for diabetic wound treatment, and they exhibited excellent antibacterial activity, demonstrating that these dressings are potential candidates for the management of infected diabetic wounds