Table 1.
Clinical and demographic characteristics of the included population.
| Boston, US | |||||
|---|---|---|---|---|---|
| Control | Early AMD | Intermediate AMD | Late AMD | Total | |
| Number, n (%) | 45 (24.3) | 32 (17.3) | 62 (33.5) | 46 (24.9) | 185 (100.0) |
| Age, Mean ± SD | 72.1 ± 8.5 | 73.7 ± 6.9 | 77.5 ± 6.7 | 81.3 ± 7.8 | 76.6 ± 8.1 |
| Female Gender, n (%) | 27 (60.0) | 21 (65.6) | 45 (72.6) | 20 (54.1) | 119 (64.3) |
| BMI, Mean ± SD | 27.1 ± 4.4 | 26.5 ± 4.2 | 27.6 ± 5.5 | 26.9 ± 4.5 | 27.1 ± 4.8 |
Race/Ethnicity, n (%)
|
42 (93.3) 1 (2.2) 2 (4.4) 0 (0.0) |
30 (93.8) 0 (0.0) 2 (6.3) 0 (0.0) |
60 (96.8) 0 (0.0) 0 (0.0) 2 (3.2) |
43 (93.5) 0 (0.0) 3 (6.5) 0 (0.0) |
175 (94.6) 1 (0.5) 7 (3.8) 2 (1.1) |
Smoking, n (%)
|
24 (53.3) 19 (42.2) 2 (4.4) |
18 (56.3) 14 (43.8) 0 (0.0) |
26 (41.9) 33 (53.2) 3 (4.8) |
16 (34.8) 30 (65.2) 0 (0.0) |
84 (45.4) 96 (51.9) 5 (2.7) |
| On AREDS Supplementation (Yes), n (%) | 2 (4.4) | 2 (6.3) | 45 (72.6) | 31 (67.4) | 80 (43.2) |
| Coimbra, Portugal | |||||
| Number, n (%) | 50 (16.7) | 57 (19.1) | 139 (46.5) | 53 (17.7) | 299 (100.0) |
| Age, Mean ± SD | 72.5 ± 5.1 | 75.0 ± 6.1 | 80.4 ± 7.5 | 85.7 ± 6.9 | 79.0 ± 8.0 |
| Female Gender, n (%) | 32 (64.0) | 34 (59.6) | 96 (69.1) | 31 (58.5) | 193 (64.5) |
| BMI, Mean ± SD | 27.0 ± 4.6 | 27.2 ± 4.3 | 27.6 ± 4.6 | 26.5 ± 4.3 | 27.2 ± 4.5 |
Race/Ethnicity, n (%)
|
50 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) |
57 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) |
137 (98.6) 2 (1.4) 0 (0.0) 0 (0.0) |
52 (98.1) 1 (1.9) 0 (0.0) 0 (0.0) |
296 (99.0) 1 (1.0) 0 (0.0) 0 (0.0) |
Smoking, n (%)
|
40 (80.0) 10 (20.0) 0 (0.0) |
49 (86.0) 8 (14.0) 0 (0.0) |
123 (88.5) 16 (11.5) 0 (0.0) |
38 (71.7) 14 (26.4) 1 (1.9) |
250 (83.6) 48 (16.1) 1 (0.3) |
| On AREDS Supplementation (Yes), n (%) | 0 (0.0) | 1 (1.8) | 2 (1.4) | 8 (15.1) | 11 (3.7) |
Legend: n—number, SD—standard deviation, BMI—body mass index, AMD—age-related macular degeneration, AREDS—Age-Related Eye Disease Study.