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. 2022 Feb 24;148(4):307–315. doi: 10.1001/jamaoto.2021.4414

Table 2. Sensitivity Analysis for Incidence Estimates of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination.

Source Incidence
Minimuma Maximumb
Cases 555 2170
Population size 185 424 899c 92 712 450d
VAERS underreporting bias, % 0 50
Incidencee 0.6 28.0

Abbreviations: SSNHL, sudden sensorineural hearing loss; VAERS, Vaccine Adverse Events Reporting System.

a

Estimates of minimum incidence were based on the 555 cases deemed to be probable SSNHL, a population size that included 1 vaccine dose per person, and the assumption that all cases were reported to VAERS.

b

Estimates of maximum incidence (the most inclusive estimates) were based on all 2170 reports of SSNHL reported to VAERS using search terms described in the Methods section, a population size that included 2 vaccine doses per person (ie, 2 opportunities to experience a COVID-19 vaccination–associated SSNHL), and the assumption that only 50% of cases were reported to VAERS.

c

One dose per person.

d

Two doses per person.

e

Per 100 000 people per year.