Table 2. Characteristics of Eyes in the Optical Coherence Tomography Angiography Progressor Group.
| Characteristic | Mean (95% CI)a | P value | ||
|---|---|---|---|---|
| Slow (62 eyes of 39 patients)b | Fast (62 eyes of 43 patients)b | Difference | ||
| Initial vessel density change, %/y | −0.47 (−0.53 to −0.41) | −1.14 (−1.22 to −1.05) | −0.67 (−0.78 to −0.56) | <.001 |
| Baseline age, mean (SD), y | 67.6 (11.4) | 70.4 (10.4) | 2.0 (15.6) | .35 |
| Sex, F/M | 21/18 | 20/23 | NA | .51 |
| Race | ||||
| African American | 14 | 6 | NA | .02 |
| Asian | 2 | 8 | NA | |
| White | 23 | 27 | NA | |
| Other | 0 | 2 | NA | |
| Self-reported hypertension, No. (%) | 25 (64.1) | 22 (51.2) | NA | .24 |
| Self-reported diabetes, No. (%) | 8 (20.5) | 4 (9.3) | NA | .15 |
| MOPP, mm Hg | 53.7 (51.9 to 55.6) | 52.9 (51.0 to 54.8) | −0.8 (−3.4 to 1.7) | .53 |
| Axial length, mm | 24.3 (24.1 to 24.6) | 24.6 (24.3 to 24.8) | 0.2 (−0.2 to 0.6) | .27 |
| CCT, μm | 538.3 (529.0 to 547.6) | 525.1 (514.6 to 535.6) | −13.2 (−27.0 to 0.7) | .06 |
| Baseline IOP, mm Hg | 14.5 (13.5 to 15.5) | 14.6 (13.5 to 15.7) | 0.1 (−1.4 to 1.6) | .90 |
| Mean IOP during follow-up, mm Hg | 14.8 (13.7 to 15.8) | 14.9 (14.1 to 15.7) | −0.1 (−1.5 to 1.3) | .85 |
| No. of eyes with glaucoma | 38 | 48 | NA | .05 |
| No. of eyes suspected of having glaucoma | 24 | 14 | NA | |
| Disease severity at baseline (24-2 VF MD), No. (%) | ||||
| Early glaucoma | 31 (81.6) | 30 (62.5) | NA | .06 |
| Moderate and advanced glaucoma | 7 (18.4) | 18 (37.5) | NA | |
| Baseline VF MD, dB | −2.3 (−3.4 to −1.3) | −4.4 (−5.8 to −3.1) | −2.1 (−3.9 to −0.2) | .03 |
| Baseline VF PSD, dB | 3.5 (2.7 to 4.2) | 5.4 (4.3 to 6.5) | 1.9 (0.6 to 3.3) | .006 |
| SSI | 67.1 (65.5 to 68.7) | 66.7 (64.6 to 68.7) | −0.4 (−3.0 to 2.2) | .76 |
| Follow-up, y | 4.1 (3.9 to 4.2) | 3.9 (3.7 to 4.1) | −0.2 (−0.4 to 0.1) | .26 |
| No. of VF visits | 7.0 (6.5 to 7.4) | 6.3 (6.0 to 6.6) | −0.6 (−1.3 to 0.0) | .04 |
Abbreviations: CCT, central corneal thickness; IOP, intraocular pressure; MD, mean deviation; MOPP, mean ocular perfusion pressure; NA, not applicable; PSD, pattern SD; SSI, signal strength index; VF, visual field; wiVD, whole-image vessel density.
a
Data are given as mean (95% CI) unless otherwise indicated.
b
For rates of wiVD change, slow indicates slower than −0.75% per year, and fast indicates −0.75% per year or faster.