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. 2021 Sep 28;122(4):4552–4580. doi: 10.1021/acs.chemrev.1c00363

Table 2. CP-Based Chemical Functionalization Approaches.

material functionalization type cell type application electrical stimulation ref
PEDOT/xylorhamno-uronic glycan (XRU84)/fibrinogen/collagen/transferrin physical absorption human dermal fibroblasts cell adhesion and spreading   (78)
PEDOT/PEG10-CDPGYIGSR (laminin-derived peptide) covalent bond rat pheochromocytoma (nerve) cells (PC-12) cell adhesion and neurite extension   (81)
titanium coated with PPy/RGD covalent bond neonatal rat calvarial osteoblasts cell adhesion   (83)
PPy/chondroitin sulfate (ECM molecule)/collagen-IV biodopant–covalent bond rat pheochromocytoma (nerve) cells (PC-12) cell differentiation yes (82)
PPyCl/ ϕT59 (phage-derived peptide) /GRGDS biodopant–covalent bond rat pheochromocytoma (nerve) cells (PC-12) cell adhesion   (80)
ITO coated with PPy/RGD biodopant human lung cancer cell A549 cell adhesion and proliferation   (88)
gold coated with PPy/CDPGYIGSRGold coated with PPy/SLPF (silk-like polymer) blend rat glial cells and human neuroblastoma cells cell adhesion   (85)
gold coated with PPy/pTS/NT3 (neurotrophin-3) blend spiral ganglion neuron explant cultures neurite outgrowth yes (91)
gold coated with PPy/pTS/BDNF blend spiral ganglion neuron explant cultures neurite outgrowth yes (92)