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. 2022 Feb 21;19(4):2460. doi: 10.3390/ijerph19042460

Table 2.

Comparison of current guidelines for solid nodule management [27].

Nodule
Dimensions
The Fleischner
Society [19]
American
College of Chest Physicians [24]
British Thoracic
Society [25]
Lung CT Screening Reporting and
Data System * [26]
<6 mm LR, no FU
HR, 12 mo FU
LR, ≤4 mm no FU
LR, >4–6 mm or HR, ≤4 mm, 12 mo FUHR, >4–6 mm, 6–12 mo FU
<5 mm, no FU5–6 mm, 12–24 mo FU <6 mm, AS (cat 2)
≥6 mm to 8 mm LR and HR,
6–12 mo FU, then re-evaluate
LR, 6–12 mo FU
HR, 3–6 mo FU
3 mo FU then 12 mo FU ≥6 mm or new nodules 4–6 mm, 6 mo LDCT (cat 3)
≥8 mm CT or PET/CT
at 3 mo
<5% risk, 3 mo FU;
5–65% risk, PET/CT and/or biopsy;
>65% risk, treatment
<10% risk, surveillance; >10% risk, PET/CT or consider resection 8–15 mm,
3 mo LDCT (cat 4A)
>15 mm (cat 4B)

* Lung-RADS® version 1.1; assessment categories release date: 2019. High-risk factors include older age, heavy smoking, larger nodule size, irregular or spiculated margins, and upper lobe location. HR = high risk; LR = low risk; mo = months; FU = follow-up; AS = annual screening; cat = category; LDCT = low-dose computed tomography.