Table 1.
Number of mutations in FGA, FGB, and FGG genes associated with both the bleeding and thrombotic phenotype summarized according to different CFD types.
| Type of CFD | Variants in FGA | Variants in FGB | Variants in FGG | Total Number of Variants |
|---|---|---|---|---|
| Afibrinogenemia | 14 | 6 | 4 | 24 |
| Hypofibrinogenemia | 3 | 5 | 7 | 15 |
| Dysfibrinogenemia | 12 | 2 | 8 | 22 |
| Hypodysfibrinogenemia | 5 | 0 | 3 | 8 |
| Total number | 34 | 13 | 22 | 69 |
CFD—congenital fibrinogen disorder; FGA—the gene coding for the fibrinogen α chain; FGB—the gene coding for the fibrinogen β chain; FGG—the gene coding for the fibrinogen γ chain.