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. 2022 Feb 16;27(4):1335. doi: 10.3390/molecules27041335
DG1 D2LONG receptor in complex with Gi1 protein
DG2 D2LONG receptor in complex with Gi2 protein
DOPC 1,2-dioleoyl-sn-glycero-3-phosphocholine
DOPE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
DOPS 1,2-dioleoyl-sn-glycero-3-phospho-L-serine
ECL Extracellular loop
GPCRs G protein coupled receptors
ICL Intracellular loop
MD Molecular dynamics
NAM Negative allosteric modulator
PAM Positive allosteric modulator
POPC 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
POPE 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
POPG 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol
PLPC 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine
R1 (1,3-benzothiazol-2-yl(2-methyl-2,3-dihydro-indol-1-yl)methanone; enantiomer R
R1G1 compound R1 bound to D2LONG dopamine receptor in complex with Gi1 protein
R1G2 compound R1 bound to D2LONG dopamine receptor in complex with Gi2 protein
R2 (4-methoxy-1-methyl-1H-indol-2-yl)(2-methyl-2,3-dihydro-1H-indol-1-yl)methanone; enantiomer R
R2G1 compound R2 bound to D2LONG dopamine receptor in complex with Gi1 protein
R2G2 compound R2 bound to D2LONG dopamine receptor in complex with Gi2 protein
S1 (1,3-benzothiazol-2-yl(2-methyl-2,3-dihydro-indol-1-yl)methanone; enantiomer S
S1G1 compound S1 bound to D2LONG dopamine receptor in complex with Gi1 protein
S1G2 compound S1 bound to D2LONG dopamine receptor in complex with Gi2 protein
S2 (4-methoxy-1-methyl-1H-indol-2-yl)(2-methyl-2,3-dihydro-1H-indol-1-yl)methanone; enantiomer S
S2G1 compound S2 bound to D2LONG dopamine receptor in complex with Gi1 protein
S2G2 compound S2 bound to D2LONG dopamine receptor in complex with Gi2 protein