Table 1.
Proteins and receptors found in platelet membranes and granules membranes [45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62].
| Platelet Membrane Leaflet | Alpha Granules Membrane Leaflet | Dense Granules Membrane Leaflet |
|||
|---|---|---|---|---|---|
| Inner | Outer | Inner | Outer | Inner | Outer |
| CadherinsBC | GPIIb/IIIaLC,BC | APPCP,PC,BC,LC | CD62PCG,BC | RAB1LiC,BC | RAL 20BlC |
| glycoprotein IVOS | IntegrinBC,OC | PDIBC,OC | MultimerinOCC | RAB 4PC,LiC,BC | |
| CD53BC,KC,LC | FibrinogenCCR,PC | PTKBlC,CCR,BC,LC | CD3626 | RAB 6BC | |
| CD37LH,AML | FYNBC,CCR,OC | FibrinogenPC,CCR, | GPIbBC,OC | RAB 8BC,OC | |
| CDC42BC,PC,LC RANTESGC,OC |
FibronectinBC,PC,LC PKCBC,LC |
PF4OC,BC SerglycinCE |
GBIIbIIIa factor VBC |
RAP 1BC,GC | |
| GpIIb/IIIaLC,BC | P-selectinLC,OC,CCR | PBPBC,LC,GC,LC | GMP140BC,LC,CCR | ||
| E-selectinBC,CCR | OsteonectinBC,PC,OS,LC | NAP-2LC,CCR,OC | CD63BC,LC,PC,LiC,CCR | ||
| CaveolinBC,CG | CD36CC,CCR,BC | SYKBC | VAMPBC,CCR,LC,PC | ||
| β-dystroglycanBC,KC, | FibrinGC,EC,LC,BlC | MultimerinCC | SNAP23CCR,BC | ||
| FilaminOC,CCR | MyosinBC,PC,PhC | CelubrevinaC | VWFCCR,BC,LC | ||
| GelsolinBlC,LC,BC | CofilinPC,BC,BlC | CD72CCR,BC | LAMP227KC | ||
| CofilinLC,P,BC | RGSCCR,LIN,LC | ||||
| Sec1BC,CCR,Ml | CIB1OC,KC,EnC | ||||
| NSFOC,CCR,LiC | TalinaCCR,PC | ||||
| syntaxins 2/4CCR | SHCBC,GC,CCR | ||||
| ActinGC,CC,BC | SRCOC,OS,PC | ||||
| CalreticulinGC,BlC,PaC | PKABC,OC,OS | ||||
| StromatinBC,LC,CC | PECAM1BC,BlC,CP | ||||
| p65Ml,BC,PC,OC | CEACAM1AML,LC,CCR,BC | ||||
| STIM1BC,CCR | CalmodulinPaC,GC,PC | ||||
| TMEM16FC | P2Y12OC,BC,LC,PaC | ||||
| CalmodulinKC,CCR,PC | P2YCCR,PC,LC | ||||
| LATBC,TC,CCR | P2Y1OC,PC,GC | ||||
| SLP-76C | MAC1LiC,OC | ||||
| p38GC,CCR,BlC | CollagenCCR,BC,TC | ||||
| DAGBC,BlCC | GalectinCCR,GC,PaC | ||||
| ARF6LC,OC,TC | WASPBC,LC,PC | ||||
| SCAR/WAVEBC,CCR | ZyxinCCR GpHb/IIIaBC |
||||
| SyntaxinCC,BC,LiC | |||||
| SNAPLiC,CCR | |||||
| SNARECC,BC,GC,CCR | |||||
| ActomyosinBC,LC,PC | |||||
| ARF6PaC,CCR,KC,LC | |||||
| SIRT1OC,PC,BC,LC | |||||
| SANREGC,CCR,PC,CC | |||||
| GPIb/IX/VBC,OrC | |||||
| VitronectinAML,CCR,PC | |||||
| ThromboplastinLC,LiC,GC | |||||
| ThrombospondinOC,CCR,CC | |||||
Type of cancer abbreviations, where the protein or receptor from platelet has been reported as a key factor: (C) cancer no specified; (BC) breast cancer; (OS) osteosarcoma; (CCR) colorectal cancer; (PC) prostate cancer; (KC) kidney cancer; (LC) lung cancer; (LH) non-Hodgkin’s lymphoma; (AML) acute lymphoblastic leukemia; (GC) gastric cancer; (OC) ovarian cancer; (BlC) bladder cancer; (Ml) melanoma; (LiC) liver cancer; (CC) cervical cancer; (PaC) pancreatic cancer; (LaC) laryngeal cancer; (TC) thyroid cancer; (EC) esophagus cancer; (PhC) pharyngeal cancer; (LIN) lymphoma; (EnC) endometrial cancer; (OrC) oral cancer.