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. 2022 Jan 28;14(2):277. doi: 10.3390/v14020277

Table 2.

Comparing self-reported local and systematic adverse events related to SARS-CoV-2 vaccination among People living with HIV (PLWH) and HIV-negative individuals.

People Living with HIV
(n = 129)
HIV-Negative Individuals
(n = 53)
p Values
n (%) n (%)
Local Adverse Events
Pain
None 87 (67.4) 31 (58.5)
Very mild 15 (11.6) 4 (7.5)
Mild 16 (12.4) 11 (20.8)
Moderate 11 (8.5) 7 (13.2)
Severe 0 (0.0) 0 (0.0) 0.30
Any of above 42 (32.6) 22 (41.5) 0.25
Redness, itch, swelling, induration, and/or skin rash
None 124 (96.1) 50 (94.3)
Very mild 0 (0.0) 1 (1.9)
Mild 2 (1.6) 2 (3.8)
Moderate 3 (2.3) 0 (0.0)
Severe 0 (0.0) 0 (0.0) 0.21
Any of above 5 (3.9) 3 (5.7) 0.59
Systematic adverse events
Fatigue, malaise, headache, dizziness, and/or lethargy
None 107 (82.9) 43 (81.1)
Very mild 5 (3.9) 3 (5.7)
Mild 11 (8.5) 4 (7.5)
Moderate 5 (3.9) 2 (3.8)
Severe 1 (0.8) 1 (1.9) 0.94
Any of above 22 (17.1) 10 (18.9) 0.77
Joint pain and/or muscle ache
None 119 (92.2) 45 (84.9)
Very mild 4 (3.1) 1 (1.9)
Mild 3 (2.3) 4 (7.5)
Moderate 3 (2.3) 3 (5.7)
Severe 0 (0.0) 0 (0.0) 0.23
Any of above 10 (7.8) 8 (15.1) 0.13
Fever
None 122 (94.6) 52 (98.1)
Very mild 2 (1.6) 0 (0.0)
Mild 4 (3.1) 1 (1.9)
Moderate 1 (0.8) 0 (0.0)
Severe 0 (0.0) 0 (0.0) 0.69
Any of above 7 (5.4) 1 (1.9) 0.27
Nausea, vomit, and/or diarrhea
None 129 (100.0) 52 (98.1)
Very mild 0 (0.0) 0 (0.0)
Mild 0 (0.0) 1 (1.9)
Moderate 0 (0.0) 0 (0.0)
Severe 0 (0.0) 0 (0.0) 0.12
Any of above 0 (0.0) 1 (1.9) 0.29
Other systematic side-effects
None 127 (98.4) 53 (100.0)
Very mild 2 (1.6) 0 (0.0)
Mild 0 (0.0) 0 (0.0)
Moderate 0 (0.0) 0 (0.0)
Severe 0 (0.0) 0 (0.0) 0.36
Any of above 2 (1.6) 0 (0.0) 0.50
Any local and/or systematic adverse events 58 (45.0) 29 (54.7) 0.23