Table 3.
Univariate | Multivariate | ||||
---|---|---|---|---|---|
HR (95% CI) | p | HR (95%CI) | P | ||
Age (years) | >60 vs. ≤60 | 1.670 (0.798–3.494) | 0.174 | ||
Gender | Male vs. Female | 1.642 (0.839–3.214) | 0.148 | ||
DM | Yes vs. No | 1.883 (1.019–3.479) | 0.043 | ||
Platelet (1000/μL) | <150 vs. ≤150 | 1.718 (0.895–3.297) | 0.104 | ||
AFP (ng/mL) | >15 vs. ≤15 | 1.909 (1.034–3.525) | 0.039 | ||
Albumin (g/dL) | <3 vs. ≥3 | 1.985 (1.045–3.772) | 0.036 | ||
Child–Pugh | B vs. A | 1.571 (0.724–3.410) | 0.253 | ||
ALBI stage | II/III vs. I | 2.876 (1.262–6.553) | 0.012 | 3.249 (1.418–7.443) | 0.005 |
BCLC stage | A vs. 0 | 1.322 (0.556–3.143) | 0.527 | ||
Tumor size (cm) | >2 vs. ≤2 | 1.428 (0.681–2.992) | 0.345 | ||
Tumor number | Multiple vs. Single | 1.375 (0.551–3.430) | 0.495 | ||
Liver cirrhosis | Yes vs. No | 2.219 (1.187–4.149) | 0.013 | ||
Histology grade | Moderate + Poor vs. Well | 1.813 (1.641–5.124) | 0.262 | ||
Microvascular invasion | Present vs. Absent | 3.606 (1.890–6.879) | <0.001 | 4.037 (2.071–7.869) | <0.001 |
DAA treatment | No vs. Yes | 1.714 (0.496–5.925) | 0.394 |
Abbreviations: HR, hazard ratio; CI, confidence interval; DM, diabetes mellitus; DAA, direct-acting antivirals; AFP, alpha fetoprotein.