Table 2.

Clinical, PCR, and Immunofluorescence Assay Results from Guinea Pigs Inoculated with Rickettsia rickettsii (Days Postinoculation) (Table view)

Animal No.	Rr-1	Rr-2	Rr-3
Fever	+ (3–11)	+ (3–8)	+ (3–9)
Weight change	−0.25%	−2.2%	+5.7%
Scrotal edema	+ (3–12)	+ (5, 7–11)	+ (8–9)
Ear dermatitis	+ (3, 5–13)	+ (6–13)	+ (7–9)
Foot dermatitis	+ (5–13)	+ (5–13)	+ (6, 9)
Liver necrosis	+	+	+
Testicular erythema	–	–	–
Lung petechiation	+	+	+
Splenomegaly	+	+	+
Ear skin PCR	+ (3–13)	+ (3–13)	+ (7–10)
Blood PCR	–	–	–
Organ PCR	+ (liver, spleen, testes, lung)	+ (liver, spleen, bladder)	+ (liver, spleen)
IFA titer	2048	1024	1024

IFA, immunofluorescence assay.