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. Author manuscript; available in PMC: 2022 Apr 14.
Published in final edited form as: Nature. 2021 Apr 14;592(7856):789–793. doi: 10.1038/s41586-021-03445-y

Extended Data Fig. 8 |. C-terminal cancer mutations affecting cyclin D1, cyclin D2 and cyclin D3.

Extended Data Fig. 8 |

a–c, Lolliplots showing the amino acid positions and their mutation numbers in the degron motif of CCND1 (a), CCND2 (b) and CCND3 (c) in pan-cancer, gathered and combined from cBioPortal (curated set of non-redundant studies)36,37, COSMIC (https://cancer.sanger.ac.uk/cosmic) 38, and Schmitz et al.39 (indicated by the dagger). Black arrows in c indicate mutations identified in haematopoietic and lymphoid malignancies. del, deletion; fs, frameshift; *, stop codon. Last accessed October 2019.