Skip to main content
. 2022 Feb 17;23(4):2208. doi: 10.3390/ijms23042208

Figure 8.

Figure 8

ACU193-targeted proteoforms develop a selective trans-retina expression that is sustained in the E20 embryo. Retinas from embryonic days E8, E14, and E20 were stained for AβOs using ACU193 (red). (A) E8 ACU193 immunoreactivity is present in the NFL, GCL, nascent IPL, and faintly in the inner INL. (B) E14 ACU193 immunoreactivity is cell specific and faintly present in the GCL with prominent staining at interface between the IPL and INL. There is a specific sub-band in the outer IPL. (C) E20 ACU193 immunoreactivity is present through all layers of the retina, prominently in the RPE but also evident in presumptive GCs, ACs, BCs, and HCs. The outer plexiform layer (OPL) is denoted with a star. Scale bar is 25 μm. N = 3.