Table 1.
Expression of miR-183 in the MSKCC [28] and PRAD-TCGA cohorts and its association with clinical variables. The Mann–Whitney test was applied to assess the statistical significance of the difference between conditions.
| Cohort | Clinical Parameter | Conditions Compared | Ratio between Conditions | p-Value |
|---|---|---|---|---|
| MSKCC | Tissue type | Primary tumor vs. Normal | 3.3 ± 2.4 | <0.0001 |
| Metastasis vs. Normal | 5.3 ± 4.1 | <0.0001 | ||
| PSA at diagnosis | High vs. Low | 1.5 ± 1.1 | 0.0182 | |
| Preoperative PSA | High vs. Low | 2.5 ± 1.9 | <0.0001 | |
| Time until recurrence (month) | Shorter vs. Longer | 1.3 ± 1.9 | 0.0195 | |
| PRAD-TCGA | Tissue type | Primary tumor vs. Normal | 4.3 ± 3.0 | <0.0001 |
| Biochemical recurrence | YES vs. NO | 1.3 ± 1.1 | 0.0404 | |
| Clinical T | T3-T4 vs. T1-T2 | 1.5 ± 1.3 | 0.0020 | |
| Gleason Score | 8-9-10 vs. 6-7 | 1.4 ± 1.0 | <0.0001 | |
| Pathologic N | N1 vs. N0 | 1.3 ± 0.9 | 0.0030 |