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. 2022 Feb 21;14(2):456. doi: 10.3390/pharmaceutics14020456

Table 1.

The in vivo NIR imaging with different nanoprobes.

Type NIR Windows Nanoprobe Dose Emission Ref.
Organic dye NIR-I IR dyes 1 μM * 650–950 nm [42,43,44,45,46,47,48,49,50,51,52]
Cy5.5 2 mg/mL 690–750 nm [53,54,55,56,57]
ICG 200 nmol/kg 750–950 nm [58,59]
MMP 20 nM 750 nm [60]
SiNC 1 mg/kg 600–800 nm [61]
NIR-II New designed IR dyes 10 mM 900–1400 nm [62,63,64]
Lanthanide-doped
nanoparticle
NIR-I Tm-doped 15 mg/kg 800 nm [65]
NIR-II Nd-doped 1 mg/mL 1060 and 1340 nm [66,67,68]
NIR-III Er-doped 5 mg/mL 1525 nm [69]
Quantum dot NIR-I Ag2S 1 mg/mL * 650–840 nm [70]
NIR-II 1000–1400 nm [71,72,73]
N,B-doped
graphene quantum dot
1 mg/mL 950–1100 nm [74]
Nanophosphor NIR-I Cr3+-doped 250 mg/mL * 650–850 nm [75]
Polymer
dot
NIR-II Aggregation-induced emission (AIE) 10 mg/kg * 800–1600 nm [76,77,78,79]

* The dose concentration is selected from one of the references.