Table 2.
Variations in demographics of the ASD children with increased intestinal permeability compared to median values in the remaining ASD children and in their US.
| Variable | Child #7 (G.B., Male) | Child #10 (S.A., Male) | ||
|---|---|---|---|---|
| Variation from Median Value in ASD 1 Children | Variation from Median Value in US 2 | Variation from Median Value in ASD 1 Children | Variation from Median Value in US 2 | |
| Age (years) | +2 (+25%) | +1 (+11.1%) | −3 (−37.5%) | −2 (−22.2%) |
| Gestational age, weeks (%) | −1 (−2.5%) | −1 (−2.5%) | 0 (0%) | 0 (0%) |
| Birthweight, kg (%) | +0.40 (+12.3%) | +0.11 (+3.1%) | +0.20 (+6.1%) | −0.09 (−2.5%) |
| Birth height, cm (%) | 0 (0%) | −1 (−1.9%) | −1 (−2.0%) | −2 (−3.9%) |
| Mother’s age, years (%) | 0 (0%) | +3 (+9.3%) | −3 (−9.3%) | 0 (0%) |
| Father’s age, years (%) | −3 (−7.5%) | +2 (+5.7%) | −6 (−15%) | −1 (−2.8%) |
| Parental age gap, years (%) | −2 (−50%) | −2 (−50%) | −2 (−50%) | −2 (−50%) |
| ADOS-2 CSS 3, score (%) | −1 (−10%) | - | +9 (+90%) | - |
| Lactulose:mannitol ratio (%) | +0.036 (+156%) | +0.036 (+156%) | +0.045 (+195%) | +0.045 (+195%) |
1 ASD, autism spectrum disorder; 2 US, unaffected siblings; 3 ADOS-2 CSS, Autism Diagnostic Observation Schedule, Second Edition, with the calibrated severity score.