Table 2.

Differentially expressed genes in fish kidney tissues.

Fish Species	Up-Regulated DEGs	Down-Regulated DEGs
Ps. maxima	Mx, IFI35, BiP, serum lectin isoform 4, serum-inducible protein kinase, ceruloplasmin, kininogen I, haptoglobin, thrombin, proteinase activated receptor 3, apolipoprotein A1	F-box only protein 25, 5-aminolevulinate synthase, phosphatidylinositol 4-kinase
S. sole	Mx, LPG2 (DHX58), ISG15, STAT1, HERC5, IFI44, IFIT-1, NUP133, TRIM21, MACPF, u-PAR, PARP14, EPSTI1, ISG12, RNF213, HERC4, MHC class II, ANXA3, RTP3, CCL19L1, SMCHD1, ACTB, GIG1, interferon-induced very large, GTPase 1, IRF3, IRF7, TLR3, MAGEL2, GILT, Herpes gp2 multi-domain protein, claudin-like protein ZF-A89, 4F2 cell-surface antigen heavy chain-like, cathepsin Z, BIRC5, rho GTPase-activating protein 11A, v-ets erythroblastosis virus E26 oncogene homolog 1, C-type lectins, MDA5, LITAF, SACS/SACSIN, TRIM39, CCL4, CCK, EBI3	COL1A2, RDH13, RPS12, LMAN1/ERGIC-53, C3, C9, CFHR3
E. moara	MHC class I, HLA-A, MR1, lysozyme, hepcidin	C3, C9, IgM, IgD, IgT/IgZ, perforin, IL1, IL2, IL8, IL11, IL12, IL15, C1, C7, C8, CCL4, CXCL13, CXCL10, CCL3, CCL19, CXCL12, CCL20, CCL25, CCR9, CXCR4, CXCR3, CXR1
D. labrax	Mx, ISG15, ISG12, RTP3, SACS/SACSIN, TRIM39, CYP11b1, STAR, CYP21a, CYP17a1, 3BHSD, CYP11a1, IFI56	CCL4, ERO1a, HYOU1, PDIA4, QORX, CXC114, VLIG
L. calcarifer	beclin-1, IP3R, CYBA, C3aR, NCF2, OSBP1, cathepsin C/CTSC, IL5Rα/CD125	CD53, MHC class Ia, CH25H, BTK, STAT5b, SOCS1