Table 3.

Differentially expressed genes in fish brain tissues.

Fish Species	Up-Regulated DEGs	Down-Regulated DEGs
G. morhua	LPG2 (DHX58), ISG15, IL8, MHC class Ia, NILT, NITR, CD3, CD8, TCR, RHOG1, ITK, FYB, LCK, granzyme, CC chemokines type-3, IL17a, MHC I complex-B2M, tapasins
S. sole	Mx, LPG2 or DHX58, ISG15, STAT1, HERC5, IFI44, IFIT-1, NUP133, TRIM21, MACPF, u-PAR, PARP14, EPSTI1, ISG12, RNF213, HERC4, MHC class II, ANXA3, RTP3, CCL19L1, SMCHD1, ACTB, GIG1, interferon-induced very large GTPase 1, IRF3, IRF7, TLR3, MAGEL2, GILT, Herpes gp2 multi-domain protein, claudin-like protein ZF-A89, 4F2 cell-surface antigen heavy chain-like, cathepsin Z, BIRC5, rho GTPase-activating protein 11A, v-ets erythroblastosis virus E26 oncogene homolog 1, MDA5, SACS/SACSIN, TRIM39, MyD88, TBKBP1/SINTAD, PKR, HERC5	COL1A2, RDH13, RPS12
H. septemfasciatus	Mx, IFI44, CCL4, CXCL13, CCL19, CCL2, CCL34, CXCL6, CXCL8, CXCL9, IL12A, IL12B, IL18B, cathepsin L, cathepsin H, cathepsin K, cathepsin O, cathepsin S, cathepsin Z, CLEC4M, CLEC10A, CD209, LGALS9, LGALS3, FUCL4, MBL, RSAD2/VIPERIN, NK-Lysin, IFIT5, GVINP1, EIF2Ak2, IFIH1, HSP30
E. malabaricus	SACS/SACSIN, CCL19, GVINP1, PD-L1, LAG3, CD3E, CD4, CD8A, RNF213, TREX, ZNFX1	NPTN, SF3B1, EWSR1, NLRX1, GNG3, MGEA5
D. labrax	Mx, ISG15, RTP3, IRF3, TLR3, C-type lectins, SACS/SACSIN, TRIM39, C3, CCL4, EBI3, IL8, RSAD2/VIPERIN, CD4, LECT2, NKTR, PTX4, C1QT1, PRL, SL, SOMA, GH, GLHA, TSH, POMC, 5HT3E, GABA, cathepsin, TLR8, TLR21, TNFa, IL1b, NCCRP-1, TCR-γ, CD8	IgM, STING, NLRC3