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. 2022 Feb 9;12(2):165. doi: 10.3390/metabo12020165

Table 1.

Summary of plasma matrix effect and sodium chloride effect on representative metabolite classes.

ZIC-c (51 Metabolites Detected) BEH (47 Metabolites Detected)
Metabolite Classes Matrix Effect Salt Effect Matrix Effect Salt Effect
Amino acids 11 (16 *) 11 (16) 14 (17) 4 (17)
Amines 2 (4) 3 (4) 2 (4) 1 (4)
Sugar and Sugar phosphate 5 (5) 4 (5) 4 (4) 2 (4)
Nucleoside and Nucleotide 10 (13) 10 (13) 8 (11) 7 (11)
Acylcarnitines 1 (2) 0 (2) 0 (2) 1 (2)
Organic acids 8 (11) 8 (11) 6 (9) 6 (9)

* Numbers within brackets represent the total metabolite number for each class. Numbers before brackets represent the number of affected metabolites. For metabolites that were measured in both positive and negative modes, matrix/salt effect is marked when either mode showed ion suppression/enhancement.