Skip to main content
. 2022 Jan 27;12(2):173. doi: 10.3390/jpm12020173

Table 1.

The Major and Minor Criteria of the Delphi and PARACELSUS score.

Major Criteria Minor Criteria
Rapidly progressing course of disease (P) Prompt alleviation of symptoms by immunosuppressants (P *)
Reddish-violaceous wound border (P) Characteristically irregular shape of the ulcer (P)
Exclusion of relevant differential diagnoses (P) Extreme pain (P)
Neutrophilic infiltrate found in the ulcer edge (D) Lesion at site of trauma (P)
Exclusion of infection (D)
Pathergy (D)
History of inflammatory bowel disease or inflammatory arthitis (D)
History of papule, pustule, or vesicle ulcerating within 4 days of appearing (D)
Peripheral erythema, undermining border, and tenderness at ulceration site; (D)
multiple ulcerations, at least 1 on an anterior lower leg (D)
Cribriform or “wrinkled paper” scar(s) at healed ulcer sites (D)
Decreased ulcer size within 1 month of initiating immunosuppressive medication(s) (D)

* The Paracelsus score contains three additional criteria: suppurative inflammation in histopathology, undermined wound border, systemic disease associated.