Figure 2.

A20 gene expression in primary human TM cells increased with selective inhibition of the TLR4 pathway. (A) RT-PCR was performed after the indicated treatments with primers specific for human A20 and the housekeeping gene GAPDH. (B) A20 gene expression was significantly elevated by TAK-242 treatment. Statistical significance was determined by one-way ANOVA with Tukey post-hoc analysis, with p < 0.05 considered statistically significant. Error bars show SEM. ** = p ≤ 0.01, *** = p ≤ 0.001.