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. 2022 Feb 9;23(4):1928. doi: 10.3390/ijms23041928

Figure 6.

Figure 6

cFN-EDA-induced fibronectin expression is attenuated with A20 overexpression. Primary TM cells were treated with the indicated Ad.5 virus and then with cFN-EDA for 48 h. (A) Representative Western blot showing fibronectin and A20 expression, with the total protein stain used for normalization. (B) Fibronectin expression was greatly induced by the addition of cFN-EDA, and A20 overexpression blocked cFN-EDA-induced fibronectin expression. Statistical significance was calculated by one-way ANOVA with Tukey post-hoc analysis, with p < 0.05 considered statistically significant. Error bars show SEM. * = p ≤ 0.05, ** = p ≤ 0.01, *** = p ≤ 0.001, **** = p ≤ 0.0001.