Table 1.
Demographics and characteristics of entire cohort.
| Demographic Characteristic | Baseline Value (at Diagnosis) |
|---|---|
| No. of patients included in cohort | 55,945 |
| Age at diagnosis | |
| Mean (SD) | 50.5 (14.2) |
| Median (Q1, Q3) | 51.0 (41, 59) |
| Sex, No. (%) | |
| Female | 32,943 (58.9) |
| Year of diagnosis, No. (%) | |
| 2010 | 3,213 (5.7) |
| 2011 | 6,871 (12.3) |
| 2012 | 4,565 (8.2) |
| 2013 | 1,903 (3.4) |
| 2014 | 39,393 (70.4) |
| Employment status,a No. (%) | |
| Full time/part time | 31,138 (55.7) |
| Retired | 10,778 (19.3) |
| Dependent/other | 6,465 (11.6) |
| Long-term disability | 106 (0.2) |
| Medicaid | 7,458 (13.3) |
| Insurance type, No. (%) | |
| Commercial | 40,208 (71.9) |
| Medicaid | 7,458 (13.3) |
| Medicare | 8,279 (14.8) |
| Elixhauser Comorbidity Indexb | |
| Mean (SD) | 0.7 (3.9) |
| Median (Q1, Q3) | 0.0 (0.0, 0.0) |
| Range | −16.0–47.0 |
| Elixhauser comorbidities,c No. (%) | |
| HIV/AIDS | 118 (0.2) |
| Alcohol abuse | 920 (1.6) |
| Anemia deficiency | 4,047 (7.2) |
| Rheumatoid arthritis | 3,221 (5.8) |
| Blood loss anemia | 237 (0.4) |
| Congestive heart failure | 1,262 (2.3) |
| Chronic pulmonary disease | 8,344 (14.9) |
| Coagulopathy | 524 (0.9) |
| Depression | 6,673 (11.9) |
| Diabetes without chronic complications | 8,241 (14.7) |
| Diabetes with chronic complications | 2,371 (4.2) |
| Drug abuse | 1,712 (3.1) |
| Fluid and electrolyte disorders | 3,267 (5.8) |
| Hypertension | 20,607 (36.8) |
| Hypothyroidism | 6,218 (11.1) |
| Liver disease | 1,329 (2.4) |
| Lymphoma | 2,663 (4.8) |
| Metastatic cancer | 5,506 (9.8) |
| Other neurological disorders | 463 (0.8) |
| Obesity | 2,380 (4.3) |
| Paralysis | 5,405 (9.7) |
| Peripheral vascular disease | 543 (1.0) |
| Psychoses | 1,195 (2.1) |
| Pulmonary circulation disorder | 37 (0.1) |
| Renal failure | 2,221 (4.0) |
| Solid tumor without metastasis | 776 (1.4) |
| Peptic ulcer disease | 37 (0.1) |
| Valvular disease | 2,221 (4.0) |
| Weight loss | 776 (1.4) |
a
Full time/part time includes Active full time, Active part time; Retiree includes Early retiree, Medicare eligible retiree, Retiree (status unknown); Other includes COBRA continuee, Surviving spouse/Dependent, Other/Unknown.
b
Elixhauser Comorbidity Index was calculated at 1 year pre-diagnosis using van Walraven et al composite (VW) score without cardiac arrhythmia.
c
The proportion of patients with each Elixhauser comorbidity was calculated at 1 year pre-index diagnosis.
Q1: First quartile; Q3: Third quartile; SD: Standard deviation.