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. 2022 Feb 15;11(2):252. doi: 10.3390/pathogens11020252

Table 1.

Epidemiological and genomic data necessary for each method. S stands for sequences, and P for phylogenetic trees. Packages are available for methods in bold. Removal time corresponds to time at which an individual becomes non-infectious, generally the culling time or end of hospitalization, and intrinsic characteristics are either number of individuals present on site or predominant animal species. Didelot et al.’s (2014) [17] method, while not based on a spatial kernel, penalized transmission trees after reconstruction if they did not respect geographical data, hence the parentheses surrounding the geographical data. Hall et al.’s (2015) [18] method could include contact data, but geographical data was used instead.

Family Method (Name) [Reference] Start of Exposure Onset of Infectiousness Sampling Time Removal Time Contact Data Geographical Data Intrinsic Characteristics Phylogenetic Tree or Sequences
Non-phylogenetic Aldrin et al., 2011 [28] X X X X S
Jombart et al., 2011 (Seqtrack) [16] X S
Ypma et al., 2012 [32] X X X S
Jombart et al., 2014 (outbreaker) [24] X S
Worby et al., 2014 [37] X S
Famulare et al. 2015 [38] X S
Worby et al., 2016 (bitrugs) [6] X X X S
Campbell et al., 2019 (outbreaker2) [30] X X S
Sequential phylogenetic Cottam et al., 2008 [2] X X X P
Didelot et al., 2014 [17] X (X) P
Eldholm et al., 2016 [39] X P
Didelot et al., 2017
(Transphylo) [40]
X P
Sashittal et al., 2020
(TiTUS) [31]
X X X X P
Simultaneous phylogenetic Explicitly phylogenetic Ypma et al., 2013 [5] X X X X S
Hall et al., 2015
(beastlier) [18]
X X (X) X S
De Maio et al., 2016
(SCOTTI) [41]
X X X S
Klinkenberg et al., 2017
(phybreak) [26]
X S
Implicitly phylogenetic Morelli et al., 2012 [23] X X X X S
Mollentze et al., 2014 [1] X X S
Lau et al., 2015 [42] X X X X S
Firestone et al., 2020 (BORIS) [29] X X X X X S
Montazeri et al., 2020 [43] X S