Table 1.
Subjects | Oral Cathinone Dose (per Kilogram of Body Weight) |
Maximum Plasma Concentration |
Terminal Elimination Half-Life | Ref. |
---|---|---|---|---|
Six male volunteers (25–35 years) |
0.8 mg (54–71 g of fresh khat leaves) | 127 ± 53 ng/mL after 2.1 ± 0.5 h | 4.3 ± 1.7 h | [21] |
Five volunteers (two females and three males) (21–30 years) |
0.8–1 mg (60 g of fresh khat leaves) |
83 ± 42 ng/mL after 1.5–3.5 h | - | [22] |
Four volunteers (two male and two female) (26–57 years) |
0.6 mg (26–59 g of fresh khat leaves) | 58.9 ± 18.8 ng/mL after 2.31 ± 0.65 h | 1.5 ± 0.8 h | [19] |
Six male volunteers (28–36 years) |
0.5 mg | 1 h | - | [23] |