Figure 2.
GPC extends lifespan and improves fitness of C. elegans. (A,B) Lifespan of worms treated with GPC (10, 50 mM) or vehicle (H2O). p values represent comparison with vehicle calculated using long rank test. (C) Body bending frequency on days 7 and 15 of adulthood in worms treated with 50 mM GPC or vehicle (n = 20). (D) Pharyngeal pumping frequency on days 6 and 12 of adulthood in worms treated with 50 mM GPC or vehicle (n = 20). For (C,D), ** p ≤ 0.01; *** p ≤ 0.0001; n.s., not significant; by two-way analysis of variance (ANOVA) followed by Bonferroni tests. Values are mean ± s.e.m.