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. 2022 Feb 14;12(2):177. doi: 10.3390/metabo12020177

Figure 6.

Figure 6

GPC reduces ROS accumulation in C. elegans with age. (A) The level of intracellular ROS increased during aging. In total, 500 nematodes on day 2 and day 6 of adulthood were harvested and measured for ROS levels with the fluorescent dye DCF. The fluorescence intensity was measured every 10 min for 2 h at 37 °C. (B,C) GPC inhibited ROS accumulation in C. elegans on day 2 (B) or day 6 (C). Nematodes on day 2 or day 6 of adulthood treated with or without GPC were harvested and ROS level was detected as in (A). (D) Illustration of GPC function in promoting lifespan and healthspan. ** p < 0.001; *** p < 0.0001; by two-way analysis of variance (ANOVA) followed by Bonferroni tests. Values are mean ± s.e.m.