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. 2022 Feb 13;23(4):2066. doi: 10.3390/ijms23042066

Table 1.

Susceptibility of Candida strains tested. EUCAST (European Committee on Antimicrobial Susceptibility Testing) breakpoints were used for Amphotericin B, Fluconazole, Voriconazole, and CLSI (Clinical and Laboratory Standards Institute) breakpoints for Caspofungin. “S”, “R”, and “I” correspond to susceptible standard dosing regimen, resistant, therapeutic failure with increased exposure and susceptible increased exposure, respectively.

Strain Amphotericin B Fluconazole Voriconazole Caspofungin
MIC (µg/mL) MIC (µg/mL) MIC (µg/mL) MIC (µg/mL)
C. albicans “S” 0.19 “S” 0.125 “S” 0.002 “S” 0.094 “S”
C. albicans “R” 0.125 “S” >256 “R” >32 “R” 0.047 “S”
C. tropicalis “S” 0.125 “S” 0.5 “S” 0.047 “S” 0.125 “S”
C. tropicalis “R” 0.125 “S” 96 “R” 1.5 “R” 0.125 “S”
C. glabrata “S” 0.125 “S” 3 “I” 0.032 “S” 0.25 “I”
C. glabrata “R” 0.5 “S” >256 “R” 8 “R” 0.25 “I”
C. lusitaniae “S” 0.75 “S” 0.38 “S” 0.012 “S” 0.125 “S”