Table 3.

Antifungal activity of L-bCts, L-hCts, L-bCtl, and D-bCtl against various strains of Candida. The percentage of growth inhibition of the indicated yeasts in the presence of different concentrations of L-bCts, L-hCts, L-bCtl, and D-bCtl was determined by broth microdilution assays. Each MIC, defined as the lowest concentration of a drug able to inhibit 100% of fungal growth, was determined using a modified Gompertz model. Experiments were performed in triplicate. “S”: sensitive, “R”: resistant. * Values obtained from Dartevelle et al. [28].

Candida Strain.	Candida albicans “S”	Candida albicans “R”	Candida tropicalis “S”	Candida tropicalis “R”	Candida glabrata “S”	Candida glabrata “R”
MIC of L-bCts (µg/mL)	30	50	50	20	>100	>100
MIC of L-hCts (µg/mL)	>240	>240	>240	>240	>240	>240
MIC of L-bCtl (µg/mL)	7.9 *	9.6	9.8	2.0	38.2	61.4
MIC of D-bCtl (µg/mL)	5.5 *	9.6	8.1	2.0	13.4	15.0